Gotu Kola waxay soo saartaa 40% Asiaticosides | 16830-15-2

Hordhaca Gotu Kola oo laga soosaaray 40% Asiaticosides:

Centella asiatica, cawska oo dhan ee la qalajiyey ee Centella asiatica, ayaa markii ugu horreysay lagu duubay "Shen Nong's Materia Medica" waxaana lagu taxay heer dhexe.

Waxay leedahay saamaynta nadiifinta kulaylka iyo qoyaanka, nadiifinta iyo yaraynta bararka. Daawaynta nabarrada, cudurrada maqaarka, iwm.

Maaddooyinka firfircoon ee ugu muhiimsan ee laga soosaaray Centella asiatica oo loo isticmaali karo isqurxinta waa asiitic acid, madecassic acid, madecassoside iyo madecassoside. wadarta guud ee glycosides ee Centella asiatica.

Waxtarka iyo doorka Gotu Kola soosaaray 40% Asiaticosides： 

Ka-hortagga bakteeriyada

Waxyaabaha laga soosaaray Centella asiatica waxaa ku jira aashitada asiitic iyo madecassolic acid, saponins-kan firfircooni waxay acidifayn doonaan cytoplasm ee unugyada dhirta, hawshan bakteeriyada waxay ka ilaalin kartaa geedka laftiisa caaryada iyo weerarka khamiirka, tijaabooyinku waxay muujinayaan in Centella asiatica.

Soosaarku wuxuu leeyahay saameyn xaddidan oo gaar ah oo ku saabsan Pseudomonas aeruginosa, Staphylococcus aureus iyo Propionibacterium acnes.

Anti-bararka

Centella asiatica wadarta glycosides waxay leeyihiin saameyn cad oo anti-bararka: hoos u dhigista wax soo saarka dhexdhexaadiyeyaasha pro-inflammatory (L-1, MMP-1), hagaajinta iyo hagaajinta shaqada maqaarka ee maqaarka, taas oo ka hortagaysa oo hagaajinaysa cilladda difaaca maqaarka.

Bogsiinta boogaha iyo nabarrada

Madecassoside iyo madecassoside waa maaddooyinka firfircoon ee Centella asiatica ee daawaynta gubashada bogsashada boogaha.

Waxay kor u qaadi karaan isku-darka kolajka iyo angiogenesis ee jirka, waxay kiciyaan koritaanka granulation iyo doorarka kale ee muhiimka ah, sidaas darteed waxay faa'iido u leeyihiin bogsashada boogaha.

Isla mar ahaantaana, asiaticoside waxay leedahay saameyn faaruq ah oo ku saabsan keratinocytes epidermal iyo vascular endothelial cells, waxayna saameyn ku yeelataa fibroblasts, taas oo kor u qaadeysa sameynta unugyada granulation ee marxaladda hore ee bogsashada nabarrada, iyo joojinta sameynta nabarrada marxaladda dambe ee saamaynta bogsashada dhaawaca.

Anti-gabowga

Soosaaray Centella asiatica waxay kor u qaadi kartaa isku-dhafka kolajka I iyo III, iyo sidoo kale dheecaanka mucopolysaccharides (sida isku-darka sodium hyaluronate), waxay kordhisaa xajinta biyaha maqaarka, firfircooni iyo cusboonaysiinta unugyada maqaarka, soo dejiso, kor u qaad iyo hagaajinta maqaarka. dhalaalaya

Dhanka kale, baaritaanka isku xigxiga DNA-da ayaa lagu ogaaday in laga soosaaray Centella asiatica ay sidoo kale kiciso hiddo-wadaha fibroblast, kaas oo kor u qaadi kara tamarta unugyada maqaarka maqaarka, ilaalinta maqaarka maqaarka iyo adkaanta, iyo jilicsanaanta laalaabyada wejiga.

Antioxidant

Asiaticoside, madecassoic acid iyo madecassoic acid dhamaantood waxay leeyihiin hawlo antioxidant cad.

Natiijooyinka tijaabooyinka xayawaanku waxay muujinayaan in madecassoside ay keeni karto superoxide dismutase, glutathione iyo peroxidase ee nabarrada marxaladda hore ee bogsashada dhaawaca.

Heerarka antioxidant-ka sida catalase, VitCHing, VitE ayaa si weyn u kordhay, heerka lipid peroxides ee dhaawaca ayaa la dhimay 7 jeer.

Cadaynta

Asiaticoside waxay joojin kartaa dhaqdhaqaaqa tyrosinase qaab ku tiirsan qiyaasta, iyo 4μg / ml asiaticoside waxay joojisaa tyrosinase 4%.