Huperzine A ｜120786-18-7

Huperzine A waa kobciye garaadka oo joojiya enzymes-ka hoos u dhiga barashada neurotransmitter acetylcholine. Waxay ka tirsan tahay fasalka cholinergic ee molecules kuwaas oo laga yaabo inay caawiyaan la dagaallanka hoos u dhaca garashada ee waayeelka.

Huperzine A waa iskudhis laga soo saaray qoyska huperzine. Waxaa loo yaqaan 'acetylcholinesterase inhibitor', taas oo macnaheedu yahay inay ka hortagto insaymka inuu jebiyo acetylcholine, taasoo keenta kororka acetylcholine.

Acetylcholine waxaa lagu magacaabaa barashada neurotransmitter waxayna sidoo kale ku lug leedahay foosha murqaha.

Huperzine A waxay u muuqataa inay tahay xarun ammaan ah. Sunta iyo daraasadaha bini'aadamka ee daraasadaha xayawaanku ma muujin wax saameyn ah oo ka yimaada qiyaasaha caadiga ah ee dheeraadka ah. Huperzine A ayaa sidoo kale loo isticmaalaa tijaabooyinka hordhaca ah si looga hortago cudurka Alzheimers.

Huperzine A waxay ku dhacdaa dareeraha cerebrospinal waxayna si fudud uga gudubtaa xannibaadda dhiigga-maskaxda.

Huperzine A waxaa sida ugu fiican loogu yaqaanaa acetylcholinesterase inhibitor. Gaar ahaan, waxay joojisaa nooca G4 ee acetylcholinesterase, kaas oo ku badan maskaxda naasleyda. Way ka waxtar badan tahay ama si la mid ah waxtar u leh ka hortagga daawooyinka kale ee acetylcholinesterase, sida tacillin ama rivastatin. Xakameeyaha ahaan, waxay leedahay xiriir sare oo loogu talagalay acetylcholinesterase. Isla mar ahaantaana, waxay leedahay kala qaybsanaan tartiib tartiib ah, taas oo ka dhigaysa nolosheeda badhkeed mid aad u dheer.

Marka lagu daro joojinta acetylcholinesterase, waxa kale oo loo arki karaa sida neuroprotective ka dhanka ah glutamate, beta amyloid pigmentation, iyo H2O2-sababtoo ah sunta.

Huperzine A waxay kor u qaadi kartaa fidinta unugyada asliga ah ee hippocampal neural (NSCs). Waxay u muuqataa inay kor u qaadayso korriinka neerfaha ee qiyaasaha noolaha.