Iopamidol|60166-93-0
Sharaxaada Alaabta:
Iopamidol, oo sidoo kale loo yaqaan iodopeptidol, iodopentanol, iopamidol, iopamidol, iodobidol, iopamisone, waa wakiilka isbarbardhigga biyaha-ilmi-la'aanta ah ee aan-ionic ahayn, kaas oo ah daawo loogu talagalay ogaanshaha sawirka. Qaab dhismeedka kiimikaadku waa xeryahooda amide ee soosaarayaasha triiodoisophthalic acid waxay leeyihiin sunta hoose ee derbiyada xididdada dhiigga iyo dareemayaasha, dulqaadka deegaanka iyo nidaamka wanaagsan, cadaadiska osmotic hooseeya, viscosity hooseeya, ka duwanaansho wanaagsan, duritaan xasilloon, iyo deiodination aad u yar ee vivo. Myelography iyo bukaanada leh khatarta sare ee falcelinta isbarbardhigga. Ka dib duritaanka xididada xididada iopamidol, waxa inta badan laga soo saaraa kelyaha. T1/2 waxay ku kala duwan tahay shaqada kelyaha, guud ahaan 2 ilaa 4 saacadood, waxaana inta badan laga soo saaraa qaabka asalka ah ee kaadida, 90% ilaa 95% ayaa laga soo saaraa 7 ilaa 8 saacadood, ku dhawaad 100% ayaa laga soo saaraa 20 saacadood. In vivo, iopamidol ma metabolized, kuma xidhna borotiinada balasmaha, mana faragalinayso isoenzymes. Sababtoo ah maadada sare ee iodine, badeecadani waxay yareysaa raajooyinka si loo gaaro ujeedada sawir-qaadaha, waxayna ku habboon tahay isbarbardhigga raajada ee cirbadeynta xididdada xididdada. Iopamidol waxa loo isticmaalaa daawaynta angiography ee kala duwan, sida arteriography cerebral. Wadnaha iyo xididada angiography waxaa ka mid ah halbowlayaasha halbawlayaasha, xididada thoracic iyo caloosha, xididada durugsan, xididada, iyo angiography kala goynta dhijitaalka ah. Iyo kaadi mareenka, kala-goysyada, fistula, xudunta laf dhabarta, ceelka iyo ventricle, halbowlayaasha visceral ee xulashada. Iskaanka la xoojiyey ee CT-ga.