L-Carnosine | 305-84-0
Sharaxaada Alaabta:
Carnosine (L-Carnosine), magaca sayniska β-alanyl-L-histidine, waa dipeptide ka kooban β-alanine iyo L-histidine, crystalline adag. Muruqyada iyo unugyada maskaxda waxaa ku jira xaddi aad u sarreeya oo carnosine ah. Carnosine waxaa helay farmashiistaha Ruushka Gurevich oo uu weheliyo carnitine.
Daraasado laga sameeyay wadamada Ingiriiska, Kuuriyada Koonfureed, Ruushka iyo wadamo kale ayaa muujiyay in carnosine ay leedahay awood adag oo Antioxidant ah oo faa’iido u leh jidhka bini’aadamka.
Carnosine ayaa la muujiyay in ay ka takhalusto radicals oxygen-ka falcelisa (ROS) iyo α-β aldehyde aan saturated lahayn oo la sameeyay intii lagu jiray diiqada oksaydhka iyada oo xad-dhaaf ah asiidhka dufanka leh ee xuubabka unugyada.
Nidaaminta xasaanadda:
Waxay leedahay saamaynta nidaaminta difaaca jirka, waxayna nidaamin kartaa cudurrada bukaannada qaba hyperimmunity ama hypoimmunity.
Carnosine waxay door aad u wanaagsan ka ciyaari kartaa nidaaminta dhismaha xannibaadaha difaaca bini'aadamka, hadday tahay difaaca unugga ama difaaca kaftanka.
Endocrine:
Carnosine waxay sidoo kale ilaalin kartaa dheelitirka endocrine ee jirka bini'aadamka. Marka laga hadlayo cudurrada endocrine iyo dheef-shiid kiimikaadka, dheellitirka saxda ah ee carnosine wuxuu nidaamin karaa heerka endocrine ee jirka.
Nafaqayn jidhka:
Carnosine waxa kale oo ay door gaar ah ku leedahay nafaqaynta jidhka, kaas oo nafaqayn kara unugyada maskaxda bini’aadamka, wanaajin kara korriinka neurotransmitters ee maskaxda, iyo nafaqaynta darafyada dareemayaasha, kuwaas oo nafaqayn kara neerfayaasha iyo nafaqaynta neerfayaasha.
Tilmaamayaasha farsamada ee L-Carnosine:
| Shayga Falanqaynta | Tilmaamid |
| Muuqashada | Ka saar budada cad ama cad |
| Aqoonsiga HPLC | Waafaqaya walaxda tixraaca ugu sarreysa |
| PH | 7.5-8.5 |
| Wareeg gaar ah | +20.0o ~+22.0o |
| Luminta qalajinta | ≤1.0% |
| L-Histidine | ≤0.3% |
| As | NMT1ppm |
| Pb | NMT3ppm |
| Biraha culus | NMT10ppm |
| barta dhalaalaysa | 250.0 ℃ ~ 265.5 ℃ |
| Qiimayn | 99.0% ~ 101.0% |
| Hadhaaga dabka | ≤0.1 |
| Hydrazine | ≤2pm |
| L-Histidine | ≤0.3% |
| Wadarta tirada saxanada | ≤1000cfu/g |
| Khamiirka & Caaryada | ≤100cfu/g |
| E.Coli | xun |
| Salmonella | xun |
