Hyaluronidase |37326-33-3
Tilmaamaha Alaabta:
Hyaluronidase waa enzim ka saari kara hyaluronic acid (hyaluronic acid waa qayb ka mid ah matrix nudaha kaas oo leh saamaynta faafinta ee xaddidaya biyaha iyo walxaha kale ee ka baxsan).
Waxay si ku-meel-gaar ah u yareyn kartaa viscosity ee walaxda intercellular, kor u faleebo subcutaneous, exudate gudaha kaydsan ama dhiig si loo dedejiyo faafin iyo fududeeyo nuugista, iyo waa qaybinta daroogada muhiim ah.
Si kiliinik ahaan loo isticmaalo sida wakiilka dawada dawada si kor loogu qaado nuugista maandooriyaha, kor loogu qaado bararka deegaanka ama daadinta hematoma qalliinka iyo dhaawaca ka dib.
| ITEM | SPEC |
| Qiimaha PH | 5.0 - 8.5 |
| Cabirka Qayb ahaan | 100% Ilaa 80 Mesh |
| Qiimayn | 98% |
| Khasaare xagga qalajinta | ≦5.0% |
| Dhaqdhaqaaqa | Aan ka yarayn 300(400-1000)IU/mg, walaxda la qalajiyey |
| Gudbinta iftiinka | T550nm>99.0% |
| Wadarta tirada saxanada | ≤1000cfu/g |
| Wadarta khamiirka & caaryada | ≤100cfu/g |
| Xaaladaha kaydinta | 2-8°C |
Sharaxaada Alaabta
Sharaxaada Alaabta:
Walax huruud ah oo cad ama khafiif ah, oo aan ur lahayn, si fudud ugu milmi biyaha, aan milmin ethanol iyo acetone, oo leh pH ugu fiican ee 4.5-6.0.
Xasilooni: Badeecada la qalajiyey wax hoos u dhac weyn kuma leh firfircoonida ka dib marka lagu kaydiyo 4 ℃ hal sano;
Marka la eego xaalada 42 ℃, hawshu waxba iskama bedelin ka dib kulaylka 60 daqiiqo;Kuleylka 100 ℃ 5 daqiiqo si aad u xajisato 80% firfircoonida;Xalalka aqueous fiirsashada hoose waxay u nugul yihiin deminta, iyo ku darida NaCl waxay kordhin kartaa xasilloonidooda;Way fududahay in la xumeeyo marka kulaylku la kulmo.
Kahortagayaasha waxaa ka mid ah ion birta culus (Cu2+, HR <2+, Fe <3+Chemalbook, Mn<2+, Zn<2+), midabada organic acid, cusbada bile, polyanions, iyo polysaccharides miisaanka molikula sare ah sida Chondroitin sulfate B, Heparin, iyo heparan sulfate.
Firfircooni waa polycation.Isku-dhafka nuugista ee 1% xalka aqueous ee 280nm waa 8. Hyaluronidase inta badan hydrolyzes N-acetyl ee hyaluronic acid- β- Inta u dhaxaysa D-glucosamine iyo D-glucuronic acid β- 1,4-bond, soo saarta hadhaaga tetrasaccharide iyada oo aan la sii dayn monosaccharides. falcelinta: hyaluronic acid + H2O oligosaccharides.
Codsiga:
1. Loo isticmaalo cilmi-baarista biochemical
2. Kiliinik ahaan, inta badan waxaa loo isticmaalaa si kor loogu qaado kala-baxa bararka deegaanka ama hematoma qalliinka iyo dhaawaca ka dib, la yareeyo xanuunka goobta duridda, iyo dardargelinta nuugista cirbadaha subcutaneous iyo muruqa durida.
3. Waxa kale oo loo isticmaali karaa adhesions xiidmaha.
Xidhmada: 1g, 5g, 10g, 30g, 50g, 100g, 500g, 1kg, 5kg, 10kg;25 kgs/bac ama sida aad codsato.
Kaydinta:Ku kaydi meel hawo leh oo qallalan.
Heerka Fulinta:Heerka Caalamiga ah.