L-Tryptophan | 73-22-3

Tryptophan (IUPAC-IUBMB soo gaabinta: Trp ama W; IUPACabbreviation: L-Trp ama D-Trp; lagu iibiyo isticmaalka caafimaadka sida Tryptan) waa mid ka mid ah 22-ka amino acids ee caadiga ah iyo amino acid lagama maarmaanka u ah cuntada bini'aadamka, sida lagu muujiyay koritaankeeda saamaynta jiirka. Waxay ku qoran tahay xeerka hiddaha caadiga ah sida codon UGG. Kaliya L-stereoisomer ee tryptophan ayaa loo isticmaalaa borotiinnada waxbarashada ama enzyme, laakiin R-stereoisomer ayaa marmar la helaa.unpeptides si dabiici ah loo soo saaray (tusaale, marine venom peptide contryphan) .Sifada qaabdhismeed ee lagu garto tryptophan waa in ay ka kooban tahay indole functional group.

Waxaa jira cadaymo muujinaya in heerarka tryptophan ee dhiiga aysan u badneyn in la bedelo iyadoo la bedelayo cuntada, laakiin in muddo ah, tryptophan ayaa laga helay dukaamada cuntada caafimaadka sida kabitaan cunto ah.

Cilmi-baaris caafimaad ayaa muujisay natiijooyin isku dhafan oo ku saabsan waxtarka tryptophan asa gargaarka hurdada, gaar ahaan bukaanka caadiga ah. Tryptophan ayaa muujisay waxtarka daaweynta noocyo kala duwan oo xaalado kale oo caadi ahaan la xidhiidha heerarka serotonin hooseeya ee maskaxda. Gaar ahaan, tryptophan waxay muujisay qaar ka mid ah ballan-qaadka ka hortagga niyad-jabka kaligiis iyo sida "kor u qaad" daawooyinka niyadjabka. Si kastaba ha ahaatee, isku halaynta tijaabooyinkan caafimaad ayaa la iswaydiiyay sababtoo ah la'aanta kontaroolada rasmiga ah iyo soo celinta. Intaa waxaa dheer, tryptophan lafteedu waxaa laga yaabaa inaanay waxtar u lahayn daaweynta niyad-jabka ama niyadda kale ee serotonin-ku-tiirsan, laakiin waxaa laga yaabaa inay faa'iido u leedahay fahamka dariiqyada kiimikaad ee siin doona tilmaamo cilmi-baaris oo cusub oo loogu talagalay dawooyinka.