Magnolia Cortex Soo saarta 2% Honokiol |35354-74-6

Magnolia officinalis soosaaray (magaca Ingiriisi: Magnolia officinalis PE), maaddooyinka firfircoon: iyo magnolol, magnolol, magnolol total phenol.Ilaha Botanical: Walxaha firfircoon ee firfircoonida bakteeriyada ee jilif Magnolia officinalis Rehder et Wilson, dawo dhaqameed Shiinees ah.

Alaabtani waa crystal budo ah oo ka baxsan-cad.Ku milmay benzene, ether, chloroform, acetone, aan biyo ku milmin, si fudud ugu milmi xalalka alkali si loo helo cusbada sodium.Kooxda phenolic hydroxyl way fududahay in la oksidhid, halka kooxda allyl ay fududahay in la maro falcelinta dheeriga ah.

Waxay leedahay saameyn gaar ah, nasinta muruqa oo dheer iyo saameyn bakteeriyada xooggan, taas oo joojin karta isku-darka platelet.

Kiliinik ahaan, waxaa inta badan loo isticmaalaa sida daawada bakteeriyada iyo fungal.Alaabtan waa in laga xidhaa meel ka fog iftiinka oo lagu kaydiyaa meel qalalan, qabow oo hawo fiican leh.

Waxtarka iyo doorka Magnolia Cortex Extract 2% Honokiol： 

Anti-bararka

Dareen-celinta bararka, phospholipids xuubka unugga ayaa sii daaya arachidonic acid (AA) oo hoos yimaada ficilka phospholipase A2.

Waxaa jira laba dariiqo dheef-shiid kiimikaad ee AA, mid waa in la abuuro prostaglandins iyo thromboxanes by ficilka cyclooxygenase (COX), kan kalena waa in la soo saaro prostaglandins iyo thromboxanes by fal cyclooxygenase (COX).Ficilka lipoxygenase (LO) wuxuu soo saaraa leukotrienes (LT).

Honokiol marka la eego qiyaasta sare waxay joojisay dhaqdhaqaaqa COX ee unugyada burburay, iyada oo la xakameynayo dariiqa dheef-shiid kiimikaadka LO.Sidaa darteed, honokiol waa laba-horjooge COX iyo LO.

Saamaynta anti-bararka ee honokiol ayaa laga yaabaa inay la xidhiidho joojinta laba dariiqo dheef-shiid kiimikaad ee AA.Intaa waxaa dheer, honokiol waxay joojin kartaa sii-deynta enzymes-ka lysosomal, waxay yaraynaysaa qulqulka derbiyada xididada ee agagaarka goobta caabuqa, waxayna joojisaa socdaalka leukocyte iyo faafinta unugyada fibreed.

Antioxidant

Magnolol iyo Honokiol waxay leeyihiin saameyn xoqid xagjir ah oo bilaash ah, kaas oo ka saari kara parahydroxyl radicals iyo hydrogen peroxide.

Isla mar ahaantaana, waxay ilaalin kartaa dhaqdhaqaaqa silsiladaha neefsiga ee mitochondrial ee ka soo horjeeda cadaadiska NADPH-ku-soo-baxa ee peroxidative, ka soo horjeeda hemolysis oksijiinta ee unugyada dhiigga cas, iyo joojinta peroxidation lipid.

Daraasado dhowr ah oo ku jira vitro iyo in vivo ayaa baadhay waxqabadka antioxidant ee Magnolia officinalis soosaaray, taas oo 1000 jeer ka xoog badan alfa-tocopherol.